"Cannot Marry"

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1 year ago

I have always loved biology right from secondary school and I think it has to do with the fact that it teaches us about living things and the environment around us. Another subject that caught my fancy too right from time was Mathematics, playing with all that numbers and equations always tickled me in the right places (don't interpret this wrongly). You would agree with me that there is a point where two subjects meet, and one of the places Mathematics and Biology met for me was at the point of probability and hereditary; Genetics.

I have the habit of always attaching a probability value to events. It has become a hobby for me, I'd always think about the probability of whatever outcome of my actions in hopes to set a realistic expectation and prepare my mind for possible outcome(s). Genetics on the other hand is just so interesting to me.

One's genotype has been an important thing to know since the advent of technology. In fact, it has been one of the most important criteria for the compatibility of marriage. Makes me wonder if the goal of marriage is procreation, more so than it is companionship. Oh well, There are five genotypes in humans, which are AA, AS, AC, SC and SS. Although, AC and SC are very rare, and I only learnt about them two years ago.

AA is considered normal genotype, while AS and AC are abnormal, while SS is SC are practically sickle cell anemia, which is a genetic disorder which affects red blood cells which transports oxygen in the body by changing its shape (reducing its surface area) and inadvertently affecting its oxygen carrying ability. The following is the compatibility test of the common genotypes with respect to procreation:

AA x AA = Compatible

AA x AS = Compatible

AA x SS = Compatible

AS x AS = Not Compatible

AS x SS = Not Compatible

SS x SS = Not Compatible

You may have noticed that I wrote above "...with respect to procreation" because I believe people can have different reason for marrying, and not necessarily because they want to procreate. If procreation is part of the marriage plans, then it is important to know the genotype of your intended.

An erroneous impression I want to debunk is people's opinion about the compatibility of AS and AS. A lot of people think that why they are not compatible is because 1/4 of their offspring will have the sickle cell anemia. It is all probability really. It just means that when two AS want to procreate, the probability of an offspring being SS is 0.25 (1/4).

I have my personal reservation about the compatibility of AS and AS. Well, is if the two parties involved are willing to gamble their peace of mind and take such risks for the sake of the 'love' right? I mean, what is worth risking it for if not LOVE (evil smirk). But on a serious note, the odds are in their favour, I mean, a 0.75 (3/4) probability of the offspring not being SS as against the probability of 0.25.

Also, the advancement of science has made it possible to know the genotype of the baby during pregnancy. But why go through all that stress? More importantly, what happens when the genotype of the baby is SS? Abortion? Surely, that will take its toll on both parents.

In conclusion, I'd say you do whatever makes you happy, and if that includes marrying someone you're incompatible with, it is up to you two to figure out and come to a conclusion on what is best for you all. Haven't been active for some days now, and that is because there are some problems that came up, making it difficult for me to be active here.

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1 year ago

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But Adam and Eve were both AA na, what happened 🀣. It is a joke though

$ 0.01
1 year ago

Mutation happened 🌚

$ 0.00
1 year ago

hahaha! I didn't go far as to genotype, I settled in with blood types. I didn't truly think about since we are already hybrid with almost the same ancestry and I wasn't faced with interracial marriage during that time, I really didn't bother. Perhaps I would should I consider marrying a foreigner, considering the existence of interracial diseases and passing on to my child is a definite no no...

$ 0.01
1 year ago

🀣🀣 That is bold. I think you should have checked to be sure. But perhaps, there is nothing to worry about.

$ 0.01
1 year ago

Some people fail to check their partner's genotype when they want to get married. Some even know the genotype but want to get married all in the name of love which is not nice. Thanks, fir bringing up this topic so that those that are not aware will know.

$ 0.01
1 year ago

Love conquereth all things 🌚

$ 0.00
1 year ago

For me, it depends on a couple on how they handle their differences and incompatibilities. And it's somehow a choice if they want to work on that things.

$ 0.01
1 year ago

That is true. It is up to them to figure it out for themselves and choose what's best.

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1 year ago

Thank God I don't have to go through all this stress, I am AA 😊 which means na only SS I go dey dodge πŸ˜‚

$ 0.01
1 year ago

HeheπŸ˜…πŸ˜… Why u det dodge SS🀣🀣

$ 0.00
1 year ago

Lol, I no want wahala na πŸ˜†

$ 0.00
1 year ago

You can still marry SS, nothing spoil.

$ 0.00
1 year ago

Abeg everything spoil, I no fit

$ 0.00
1 year ago

It depends on the people. Whether they could deal with incompatibility, especially in marriage.

$ 0.01
1 year ago

I agree with you on that.

$ 0.00
1 year ago

In the end, the decision is up to the two people who want to marry, and sickle cell anemia is not as dangerous as many other diseases that can be mutations or undisclosed, but the possibility of their existence exists, then 0.25% risk, for someone you love is worth it, But the child's suffering in the future is not worth it, oh it's complicated and varied

$ 0.01
1 year ago

I guess you are right, it falls down to what the couple wants. Been a while Doc Lara.

$ 0.00
1 year ago

Yeah I know and I'm sorry about this, but I have exams and sadly I haven't finished yet I still have a whole month of exams yet

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1 year ago

Oh, that is okay. Focus on that. We aren't going anywhere eh? I wish you success in your exams.

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1 year ago

Thanks a lot dear πŸ€—

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1 year ago

Gsimetimes it makes me wonder why some people still believe that there is no God... Is it just mere coincidence that AS which is the best genotype is the most predominant in the world's population as ober 60% of the populace are AA. What if it was the other way roundd, in the case if AS?

$ 0.01
1 year ago

Well, the odds favour AA, so it is understandable if majority of the population are AA. In fact, I think mutation brought about S in this equation.

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1 year ago

Yeah I know that,but it couldn't have happened by chance... Theres definitely a greater power that ccordinates all these processes. I bet they don't occur spontaneously as science would make us believe

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1 year ago

You know, there are many theories about life itself, and the big bang theory is one of the, as is the creationist theory .

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1 year ago

Before I meet my partner personally I made a research about our compatibility as I am concerned about the infertility. Because incompatible blood cells of two different person's, can't makes a woman pregnant, and if ever the woman gets pregnant there's a possibility of disability or miscarriage. I think it was the same with marriage. If both of you aren't compatible, the marriage won't work, and if you push to it the possibility of failed marriage was possible. However as you said it's still depend upon the two persons involve.

That is why I also love biology but not mathπŸ˜‚πŸ˜‚.

$ 0.02
1 year ago

Fertility is another important factor to consider, although, advancement in science can help fertility problems more than genotype. It is good you did your own research.

$ 0.00
1 year ago

Yes science can help the infertility issue, but only rich people can afford that procedure πŸ˜…, and so considering the natural method like knowing the compatibility is better. I really made the research because I don't wanna expect for nothing. Luckily we are compatible πŸ˜†.

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1 year ago

Haha. It is good that you left nothing to chance such meticulousness is good.

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1 year ago

That's very sad if the genotype is SS.. But I guess, only rich people can take this kind of test ..so ordinary people don't really care about it πŸ˜…

$ 0.01
1 year ago

I guess you are right, but I would expect it to be affordable for middle class people too.

$ 0.00
1 year ago