Painkillers Mode of Action

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As we all know that painkillers are used to treat pain. Painkillers are available in so many types in pharmacies, and they all come in different brand names. 


Painkillers can be taken in the form of liquids, tablets, or capsules from the mouth. By injection Anti-inflammatory drugs (nsaids) through the posterior passage (rectum) as suppository. There are different non steroidal  anti-inflammatory drugs such as ibuprofen, diclofenac and naproxen. 

Aspirin is also a non steroidal drug. However, it is mainly suggested in small doses to help prevent blood clotting; for example, especially for those who have had a heart stroke in past life.

Opioids are sometimes called narcotic drugs and although they reduce pain, they do not fall into the category as painkillers available without aspirin and tylenol.This specific medication use to treat severe pains in the body, and this medication is a prescription medication so, not everyone can buy this without prescription. In addition to overcoming pain, opioids can make some people feel relaxed, happy or elevated and seem addictive. Additional side effects may include slow breathing, constipation, nausea, confusion, and drowsiness.

Naproxen is such a kind of medicine that reduces inflammation and pain in the joints and muscles. It is used to treat joint diseases, such as rheumatoid arthritis, osteoarthritis and gout. It is also used for muscle and bone pain. The method of operation of painkillers is that our body is full of nerve heads like skin and tissues are full of nerve heads. Some of these nerve ends can feel pain, such as burning or killing. When our body cells are injured or damaged, they emit chemicals called prostaglandins.

From Unsplash

Painkillers interfere with pain messages sent to the brain through nervous heads, affecting the brain, spinal cord, or injured part. Non-steroidal anti-inflammatory drugs produce some unique enzymes such as cox-1 and cox-2, and these enzymes block the creation of prostaglandins.  So, tissue does not swell, and the message of pain coming from the nerves becomes silent without prostagdon. 

Risks

Painkillers can be harmful, especially when taken in the wrong way. Overdose, either intentionally or accidentally, poses a very real risk when taking any otc or prescription pain medication.

Ibuprofen, aspirin, and naproxen have the properties of blood-thinning. This isn't a problem for most people, but for those already on blood-thinning medications, it can be an issue by raising blood pressure. 

Take Enough Amount of Water with Medicine 

A little sip can't be enough. The amount of water should be good according to the portion of medicines, and approximately 1 glass of water with one painkiller is necessary for full dissolving of medicines. Water helps your mouth absorb the medicine into your stomach and small intestine and give the required action. Taking medicines without enough water blocks the medicine to work properly as well as in this way medicine harms your liver more.


Milk interferes with the absorption of various antibiotics such as tetracycline, dairy products, antibodies, and iron production prevents some medicines from being properly absorbed in the body. If the medicine is not properly absorbed, it can be less effective. So, always try to take medicine with plain water.

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