Marasmus:
Child reacts to the stress of PEM and secretes cortisol, which mobilises protein from muscle and subcutaneous tissue to amino acid pool resulting in wasting with no oedema and no hepatomegaly.Raised cortisol level lowers growth hormone and so the child is stunted.Marasmus is said to be well adapted to the stress of deficit in protein and calories.The signs and symptoms observed in marasmic child are the following :
Severe growth retardation
Loss of subcutaneous fat
Severe muscle wasting
The child looks appallingly thin and limbs appear as skin and bones
Shrivelled body
Wrinkled skin
Bony prominence
Associated vitamin deficiencies
Failure to thrive
Irritability, fretfulness and apathy
Frequent watery diarrhoea and acid stools
Mostly hungry but some are anorectic
Dehydration
Temperature is subnormal
Muscles are weak
Oedema and fatty infiltration are absent
Marasmic Kwashiorkor:
The child shows a mixture of some of the features of marasmus and kwashiorkor. This is due to the varying nature of the dietary deficiency and the social factors responsible for the disease and presence or absence of infections.
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Nutrition Science by B. Srilakshmi
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