Notochord ( Embryology)

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Notochord formation

🤓āĻ†āĻœ āĻ†āĻŽāĻ°āĻž āĻĒā§œāĻŦā§‹ Notochord āĻ¨āĻŋā§Ÿā§‡āĨ¤ āĻ¯āĻĻāĻŋāĻ“ āĻ¯āĻ–āĻ¨ āĻ†āĻŽāĻŋ embryo āĻĒā§œāĻ¤āĻžāĻŽ, āĻāĻŸāĻž āĻ–ā§āĻŦ āĻ‡ āĻĒā§āĻ¯āĻžāĻšā§‡ āĻĢā§‡āĻ˛āĻ¤ā§‹āĨ¤ 😰

☝āĻĒā§āĻ°āĻĨāĻŽāĻ¤ āĻ†āĻŽāĻ°āĻž āĻœāĻžāĻ¨āĻŋ āĻ¯ā§‡ , epiblast and hypoblast āĻĻā§āĻ‡āĻŸāĻŋ layer āĻĨā§‡āĻ•ā§‡āĻ‡ āĻ¤ā§ˆāĻ°āĻŋ āĻšā§Ÿ, 3 germ layers.. 💁

🚩 Epiblast is converted into amniotic cavity

🚩 Hypoblast is converted to yolk sac.

đŸŒŧāĻāĻ–āĻ¨ āĻāĻ‡ epiblastic cell āĻ—ā§āĻ˛āĻž embryo āĻāĻ° caudal region āĻĨā§‡āĻ•ā§‡ hypoblast āĻ āĻ¯ā§‡āĻ¤ā§‡ āĻĨāĻžāĻ•ā§‡āĨ¤ āĻ¯āĻžāĻ° āĻĢāĻ˛ā§‡ āĻ¸ā§‡āĻ–āĻžāĻ¨ā§‡ āĻ¤ā§ˆāĻ°āĻŋ āĻšā§Ÿ āĻāĻ•āĻŸāĻž groove āĻŦāĻž āĻ˛āĻŽā§āĻŦāĻž āĻ—āĻ°ā§āĻ¤āĨ¤

đŸŒē āĻ¸ā§‡āĻŸāĻžāĻ•ā§‡āĻ‡ āĻŦāĻ˛āĻž āĻšā§Ÿ Primitive Streak

🚩It appears at 2nd week of development which is a longitudinal ridge at the dorsal surface of germ disc..

🚩āĻāĻ°āĻĒāĻ° āĻāĻ‡ Primitive streak āĻāĻ° cranial end āĻ āĻ¤ā§ˆāĻ°āĻŋ āĻšā§Ÿ āĻ†āĻ°ā§‡āĻ•āĻŸāĻŋ shallow rounded groove āĻ¯āĻžāĻ° āĻ¨āĻžāĻŽ Primitive Node. 💁

🚩āĻāĻ–āĻ¨ āĻ†āĻŽāĻ°āĻž āĻœāĻžāĻ¨āĻŋ āĻ¯ā§‡, germ disc āĻāĻ° cranial end āĻ āĻ†āĻ›ā§‡ prechordal plate. āĻāĻŦāĻ‚ caudal end āĻ āĻ…āĻŦāĻ¸ā§āĻĨāĻŋāĻ¤ primitive streak with primitive node..

🚩 āĻāĻĻāĻŋāĻ•ā§‡ epiblastic cell āĻ—ā§āĻ˛āĻž hypoblast āĻ āĻ¯āĻžāĻ“ā§ŸāĻžāĻ° āĻĢāĻ˛ā§‡ āĻ¤ā§ˆāĻ°āĻŋ āĻšāĻ˛ā§‹ āĻ¤āĻŋāĻ¨āĻŸāĻŋ āĻ˛ā§‡ā§ŸāĻžāĻ°āĨ¤

1. Ectoderm

2.Mesoderm

3.Endoderm

🚩 Mesoderm layer āĻāĻ° āĻ­āĻŋāĻ¤āĻ° just below the primitive node āĻ¤ā§ˆāĻ°āĻŋ āĻšāĻ¤ā§‡ āĻĨāĻžāĻ•ā§‡ Notochordal plate...

It is situated between the primitive node and prechordal plate.. āĻ…āĻ°ā§āĻĨāĻžā§Ž, primitive nodeāĻāĻŦāĻ‚ prechordal plate āĻāĻ° āĻŽāĻ§ā§āĻ¯āĻŦāĻ°ā§āĻ¤ā§€ āĻ¸ā§āĻĨāĻžāĻ¨ā§‡ mesoderm layer āĻ āĻ…āĻŦāĻ¸ā§āĻĨāĻŋāĻ¤ tube like structure āĻ‡ āĻšāĻ˛ā§‹ Notochord...🍁

🚩🚩 āĻāĻ–āĻ¨ āĻĻā§‡āĻ–āĻž āĻ¯āĻžāĻ• āĻāĻ° function āĻ—ā§āĻ˛āĻžāĻƒ 🍀

1. It forms the central axis of embryo.

2. It helps in neural tube formation

3. It provides central axis around which vertebrae and intervertebral disc develop..

🚩Fate of notochord: it disappeares..

only 2 ramnats remain:

1. Nucleus pulposus of Inter vertebral disc

2. Epical ligament of odontoid process of 2nd cervical vertebrae..

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