Community Medicine (Polio)

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What is poliomyelitis??🤷‍♀

🔴🔴Poliomyelitis is an acute viral infection caused by an RNA virus which is primarily an infection of the human alimentary tract but the virus may infect the central nervous system in a very small percentage(1%) of cases in varying degrees of paralysis and possibly death🔴🔴

āĻāĻŦāĻžāĻ° āĻ†āĻ¸āĻŋ Polio āĻāĻ° Epidemiology āĻ¨āĻŋā§Ÿā§‡đŸ‘‰đŸ‘‰

🔷Agent factors:

âŦ›Agent:Poliovirus(It is an RNA enterovirus)

âŦ›Reservoir of infection:Man is the only known reservoir of infection.Most infections are subclinical.

âŦ›Infectious material:Faeces & oropharyngeal secretions of an infected person

âŦ›Period of communicability :7-10days

🔷Host factors:

◾Age:Occurs in all age group but children are more susceptible than adults

◾Sex:Male:female=3:1

◾Risk factors:

👉Trauma

👉Fatigue

👉Intramuscular injection

👉Operative procedures such as tonsillectomy

🔷Environmental factors:

◾Season:more in rainy season

◾Contaminated water,food,and flies and overcrowding are important contributory factors

🔷Mode of transmission :

◾Faeco-oral route:Main route of spread in developing countries

◾Droplet infection:More important during epidemic and where sanitation is good(developed countries)

🔷Incubation period:7-14days(Range 3-35days)

āĻāĻŦāĻžāĻ° āĻœā§‡āĻ¨ā§‡ āĻ¨ā§‡āĻ‡ "CLINICAL SPRECTRUM OF POLIO"💁💁

1âƒŖIn-apparant polio/Subclinical infection:

🔸This occurs in 91-96%of infections

🔸No sign & symptom

🔸Virus can be isolated from stool

🔸Rising antibody titre

2âƒŖAbortive polio/minor illness:

🔸This occurs in 4-8% infections

🔸Mild or self-limiting illness due to viraemia

🔸Patient recovers quickly

🔸Diagnosis can't be made clinically

🔸Virus can be isolated from stool

🔸Rising antibody titre

3âƒŖNon-paralytic polio:

🔸1%infection

🔸Sign & symptom-stiffness and pain in the neck and back

🔸Disease last for 2-10days.Recovery is rapid.

🔸Similar to aseptic meningitis

4âƒŖParalytic polio:

🔸Occurs in <1% of infections

🔸Invades CNS & causes asymmetrical flaccid type of paralysis

🔸A history of fever at the time of onset of paralysis is suggestive of polio

5âƒŖOther associated symptoms:

🔸Malaise

🔸Constipation

🔸Anorexia

🔸Abdominal pain

🔸Nausea

🔸Headache

🔸Sore throat

āĻāĻ–āĻ¨ āĻ†āĻ¸āĻŋ āĻ•ā§€āĻ­āĻžāĻŦā§‡ Polio āĻ•ā§‡ Prevent āĻ•āĻ°āĻž āĻ¯āĻžā§ŸđŸ‘‰đŸ‘‰

Immunization is the sole effective means of preventing poliomyelitis.āĻāĻœāĻ¨ā§āĻ¯ ā§¨āĻ§āĻ°āĻ¨ā§‡āĻ° vaccine āĻŦā§āĻ¯āĻŦāĻšāĻžāĻ° āĻ•āĻ°āĻž āĻšā§Ÿā§‡ āĻĨāĻžāĻ•ā§‡âžĄ

1âƒŖInactivated(Salk) polio vaccine (IPV)

2âƒŖOral(Sabin) polio vaccine(OPV)

āĻāĻĻā§‡āĻ° Dose schedule āĻšāĻ˛âžĄ

🔴OPV:total 3dose āĻ¯ā§‡āĻ—ā§āĻ˛āĻž 4week interval āĻ 6,10,14 week āĻ āĻĻāĻŋāĻ¤ā§‡ āĻšāĻŦā§‡ ā§¨āĻĄā§āĻ°āĻĒ āĻ•āĻ°ā§‡

IPV:total 2dose āĻ¯ā§‡āĻ—ā§āĻ˛āĻž 8week interval āĻ 6,14week āĻ āĻĻāĻŋāĻ¤ā§‡ āĻšāĻŦā§‡ .1ml āĻ•āĻ°ā§‡đŸ”´

āĻāĻĻā§‡āĻ° āĻŽāĻ§ā§āĻ¯ā§‡ āĻĒāĻžāĻ°ā§āĻĨāĻ•ā§āĻ¯ āĻœāĻžāĻ¨āĻ¤ā§‡ āĻ¨āĻŋāĻšā§‡āĻ° ā§§āĻ¨āĻ‚ āĻ›āĻŦāĻŋ āĻĻā§‡āĻ–ā§āĻ¨đŸ’

āĻ–ā§āĻļāĻŋāĻ° āĻ•āĻĨāĻž āĻšāĻšā§āĻ›ā§‡ Polio āĻ•ā§‡ eradicate āĻ•āĻ°āĻž āĻ¯āĻžā§ŸđŸ¤—āĻ¤āĻžāĻšāĻ˛ā§‡ āĻœā§‡āĻ¨ā§‡ āĻ¨ā§‡āĻ‡ āĻ•ā§‡āĻ¨ āĻ•āĻ°āĻž āĻ¯āĻžā§Ÿ 🤷‍♀👉

✅Man is the only host

✅No long term carrier state

✅OPV is cheap & easy to administer

✅Half-life of excreted virus is 48hours & spread can only occur during this period

✅Live attenuated viruses in OPV multipy in intestine & interrupt the transmission of the wild viruses

✅OPV induces both humoral & intestinal immunity

✅Antibody is quickly produced

✅Viruses can be transmitted from a recently vaccinated child to close contacts who have not immunized

✅No insect,vector,animal is involved in the transmission of disease

✅Having international cooperation(NID)

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