Drug resistance:
Define: When the MIC level of a drug is exceed >10 times than the original MIC for a susceptible organism just to inhibit their growth, then the bacteria are said to be resistant to that drug.
Prevention of drug resistance:
1.Restricting the drug and use appropriate antibiotic after C/S
2.Avoidance of indiscriminate
3.use of antibiotic Use of antibiotic in appropriate dose and for proper duration
4.Constant monitoring in resistant cases both inhospital & community.
5.Using antimicrobial combination in appropriate circumstances eg TB.
6.Limitation of the use of newer antibiotic so long as the currently use drug are effective.
it is an important issue now a days. I have seen many times that children are restricted to some of antibiotics. we need the complete the dose schedule.