More than one-third of modafinil users report headache as a side effect, with nausea coming in second (11 percent of people taking Modafinil). Less than 10% of clinical trial participants reported other side effects included rhinitis, nervousness and anxiety, back pain, insomnia, and gastrointestinal complaints (such as diarrhoea and indigestion).
Modafinil UK can reduce the efficacy of hormonal contraceptives by interfering with the enzymes that convert these hormones into their active form.
Life-threatening rashes, such as Stevens-Johnson Syndrome (SJS) and drug-induced hypersensitivity syndrome, have occurred infrequently with Modafinil (DRESS). The majority of reactions are most likely allergic in nature. Seek quick medical attention if you develop any signs of a rash or other allergic reactions (such as facial swelling, difficulty breathing).
Even though Modafinil has been on the market for over 20 years, experts are unsure how long-term use affects the brain. Some are concerned about chronic sleep disturbance, future sleep ability, increased antisocial tendencies and emotion suppression, as well as withdrawal symptoms.