COVID research: A year of scientific milestones!

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2 years ago
Topics: COVID-19
A cell infected with particles (yellow; artificially coloured) of the SARS-CoV-2 variant called B.1.1.7, which is more easily transmitted than other version of the virus. Credit: National Institutes of Heath/ Science Photo Library

For just over a year of the COVID-19 pandemic, Nature highlighted key paper and preprints to help readers keep up with the flood of coronavirus research. Those highlights are below. For continued coverage of important COVID-19 developments, go to Nature's news section.

A health worker prepares a dose of the AstraZeneca COVID-19 vaccine for a woman in Hasland, UK. Credit: Oli Scarff/AFP/Getty

30 April- One vaccine dose can nearly halve transmission risk

A single dose of the COVID-19 vaccine made by either Pfizer or AstraZeneca cuts a person's risk of transmitting SAR'S-Cov-2 to their closest contacts by as much as half, according to an analysis of more than 365,000 households in the United Kingdom

Although the vaccines have been shown to reduce COVID=19 symptoms and serious illness, their ability to prevent coronavirus transmission has been unclear. Kevin Dunbar, Gavin Dabrera and their colleagues at Public Health England in London looked for cases in which someone became infected with SARS-CoV-2 after receiving a dose of either vaccine (R. J. Harris et al. Preprint at knowledge Hub Documents 2021). They then assessed how often those individuals transmitted the virus to house contacts.

The team found that people who had been vaccinated for at least 21 days could still test positive for the virus. But virus transmission from these individuals to other in their households was 40-50% lower than transmission in households in which the first person to test positive had not been vaccinated. Results for the tow vaccines were similar. The findings have not yet been peer reviewed.

A person with Covid-19 lies in an intensive-care unit in Santiago. Credit: Martin Bernetti/AFP/Getty

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