For life #Respiratory_system #Topic: Transport of Co2 As Pratasha was walking towards Chawkbazar from War Cemetery, he saw some piles of dirt near Chawkbazar. - Seeing the dirt, I thought why not remove them? From here the disease will spread germs, people will get sick, for harmful people. 😰 Suddenly in the head of expectation - well, such an unnecessary thing is produced in our body, how is it eliminated? In fact, how to eliminate CO2 As soon as Pratasha went to their house in the alley next to AK Khan, Gaiton opened .... 6 Now he started reading Transport of CO2 Forms of co2 that are transported in the blood: 1 / In the dissolved state-7% 2 / In the form of HCO3 a) KHCO3 in RBC b) NaHCO3 in plasma 3 / In combination with Hb and plasma proteins forming carbamino compounds-23% a) Carbamino-Hb in RBC b) Carbamino-protein in RBC and plasma. Transport mechanism of co2 from tissue to lung: 1⃣Diffusion of co2 from tissue to lung: 🔸PCO2 of tissue cell = 46mmHg COPCO2 of interstitial fluids = 45mmHg DifferencePressure difference = (46-45) = 1 mm Hg For a pressure difference of 1 mm, CO2 moves from the cell to the interstitial fluid. Co2 can diffuse 20 times faster than oxygen, which means it has more affinity. 2⃣Diffusion of CO2 from the interstitial fluid into the blood: COPCO2 in interstitial fluid = 45 mm Hg COPCO2 in arterial blood entering the tissue = 40mmHg Pressure difference = (45-40) = 5mm Hg CO2 moves from the interstitial fluid to the blood for a pressure difference of 5 mm. Basically, PCO2 in tissue cell is 46 mm Hg. Tissue has initial fluid e pressure. 45 mm Hg means CO2 will go from tissue cell to interstitial fluid. The pressure of the interstitial fluid is 45 mmHg and the pressure at the arterial end of the tissue is 40 mm Hg. SO becomes equal to the blood of interstitial fluid and venous end. 3⃣Transport of CO2 in the blood: NIn the form of dissolved state: About 7% CO2 is normally transported. FormIn the form of HCO3: About 70% CO2 is transported in this form. In the form of carbamino compounds: About 23% CO2 is transported in this form. OstMost of the CO2 Why is transported through HCO3? Because to cross the shortcut path quickly. Rbc contains an enzyme called carbonic anhydrase, which can break down H2CO3 to make HCO3. .CO2 contains water which eventually turns into H2CO3. Carbonic anhydrase breaks down H2CO3 to form H2O and CO2 so very quickly co2 is converted to HCO3. Then the chloride shift mechanism is the HCO3-RBC that is formed in large quantities to maintain ionic equilibrium. The mechanism is that CO2 diffuses into RBC. CO2 binds to H2O and converts to H2CO3 in the presence of carbonic anhydrase. H2CO3 breaks down again to H + and HCO3. H + becomes HHb with Hb. 70% HCO3- exits RBC cells and enters plasma. And CL- enters plasma from RBCs in the presence of bicarbonate chloride carrier protein Then again through the reverse chloride shift mechanism CL-RBC will be released from the cell and CO2 will diffuse in the lung alveoli. 4⃣Transport of CO2 from blood to lungs: PCO2 in the arterial end of the pulmonary capillary = 45mmHg PCO2 of the alveolar air = 40mmHg Pressure difference = (45-40) = 5mmHg CO2 will move from the blood to the alveoli for a pressure difference of 5 mm. Forgive the mistakes you will see with beautiful eyes🤗
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