Poison of dhatura

Toxicology Datura Poisoning Zeba and Jui are sitting on the verandah talking on a lazy afternoon of Lockdown. Zeba is older than the two sisters, studying medicine, MBBS in 3rd year. And younger sister Jui is in class 9. While telling the story, Zeba asked Jui about her studies, "How are you doing? What did you study all day today?" Xu said he has read the novel for thousands of years today. Xu asked Zeba about the matter: "I read in the novel for a thousand years that Chamiron Bibi Dhutura died after eating flowers, is this possible? Do you know anything !? Zeba: Yes, it is possible. Jui: How is that possible? Does anyone die by eating flowers!? Zeba: You are a small man, if you say this, you will understand !? Jui: Yes, I understand, tell me Zeba: What can I do with you, you have so much curiosity. Well listen then how is this possible ..... There are two types of dhutura species in all of Bangladesh -Datura Fastuosa: Dark purple flower, it is poisonous. -Datura alba: White flower, it is not poisonous. Jui: Well, then Chamiron Bibi died after eating this purple flower? Zeba: Yes. Well listen ... (I think, in this gap, my dhutura item will be revised:) Dhutura one: -Stupefying poison (People start fooling when they play this) -Deliriant poison (People start talking nonsense) -Road poison 👉 Now listen to its Active principles, -Hyoscine -Hyoscyamine -trace of atropine Fatal dose: Powder seed- 0.6 to 1gm 🏀 Crush seed- 100 to 125 seeds. 👉fatal period- 24hours. Jui: I don't understand what you are saying Well stay, I will not listen Hey, listen to the stupid sign symptoms now, What are the sign symptoms? Answer: Listen to what happens when you play this ...... -Dryness of mouth -Difficulty in swallowing -Diluted pupil -Diplopia -Dry hot skin, face are flushed -Drunkenness -delirium and hallucination -Dleep -Ludicrous movement -Morton sign -burning pain in the stomach -tachycardia -tachypnoea -photophobia -Death due to respiratory failure. 👉 circumstances of poisoning: -crushed powder used by criminals for stupifying a victim prior to robbery, rape or kidnapping. (Road poison) -Occasionally used for suicide. -Homicide is rare. -Used as abortifacient. -It has aphrodisiac action. Xu: Well, I'm leaving. Answer: I heard so much, and I will leave without hearing the treatment? Listen a little ....

Treatment: -Emetics -Repeated stomach wash with weak solution of tannic acid. -Give activated charcoal -Wash out the lower bowel frequently by enema -Physostigmine one mg -Pilocarpine nitrate Delirium can be prevented by bromide and short acting barbiturate -Symptomatic treatment. এখন শুন, এই ধুতুরা ফুল খেয়ে মারা যাওয়ার পর ছমিরন বিবির শরীরে কি কি change হয়েছিল, 👉 postmortem appearance of datura poisoningঃ -Sign of asphyxia with congested organ. -Fragment of datura seed may be present in the stomach. -Atropine can be found after long time. জুইঃ আর শুনবো না,আমাকে যেতে দাও🙄। জেবাঃ আর একটু শুন না, ধুতুরার বীজের মত আবার capsicum এর বীজ আছে। দুইটাকে আলাদা করবি কিভাবে তুই? জুইঃ কিভাবে করবো?🤔 জেবাঃ এজন্যই তো শুনতে বলছি। শুন..... 🏀Datura seed: 1.Size: large and thick 2.Shape: kidney shape 3.Colour: Yellowish brown 4.Smell: Odourless 5.Surface: Multiple depression are present. 6.Convex margins: Two ridges are present on convex margins. 7.Taste: Bitter in taste. 🏀Capsicum seed: Size: Small and thin Shape: Rounded Colour: Pale yellow Smell: Pungent, irritating smell. Surface: Surfaces are smooth. Convex margin: No doubt ridges on the margins. Taste: Burning, irritating taste. জুইঃ আমি আর শুনবো না বলেই দৌড়ে রুমে চলে গেলো........ জেবা এইবার মনে মনেই পড়তে থাকলো.......... Morton sign এ যেন কি কি ছিলো🤔..... হ্যাঁ মনে পড়েছে, 🎯Hot like 'Hare' : Rise temperature (even may rise as 107°F) 🎯Red like 'Beet' : Flushing of face followed by dilatation of cutaneous vessels. 🎯Blind like 'Bat' : Conjunctiva suffused, pupils dilated, photophobia, diplopia,loss of accommodation of near vision,temporary blindness and drowsiness leading to coma. 🎯Mad like 'Hen': May have low muttering delirium, visual and auditory hallucination, ludicrous movements, drunken gait. 🎯Dry like 'Bone': Mouth and throat will be dry,intense thirst, nausea,vomiting,dysphagia, dyspepsia, retention of urine.. 👉Ludicrous movement কি যেনো পড়েছিলাম,🙄 ও হ্যাঃ- In the phase of excitation of acute datura poisoning,ludicrous movement is observed. 🏀It is characterized byঃ- 🎯The patient tries to run away from bed. 🎯He picks up bed-sheets. 🎯He may ping rolling movement. 🎯He draws imaginary threads from the tip of a finger and threads imaginary needles.