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I’ve actually experienced this.
I killed a huge Timber Rattler which was threatening our cat. Knowing that rattlesnake meat is regarded as a delicacy, I decided to fry it up!
I cut off the head, then skinned and gutted the snake. Very much like cleaning a fish.
As I final step, I washed out the cavity under a stream of cold water.
And that was enough to fire the nervous system of the snake, which suddenly and violently writhed in my hands. Scared the daylights out of me! I threw the carcass into the freezer, slamming the door shut behind me.
The video at this web site shows (with a fish) how this happens: